Everything you need to know about the Cass report (2024)

An eagerly-awaited review into the care of gender-questioning children in England and Wales today tore apart current practices.

Dr Hilary Cass's near 400-page report states children have been let down by a lack of research on medical interventions like powerful puberty blockers.

And guidelines for treating children who want to swap gender also aren't evidence-based, therespected paediatrician said.

Her catalogue of damning findings will be used as ammunition to overhaul one of the most controversial areas of modern medicine both in the UK and the rest of the world.

Here, MailOnline, answers your questions on the Cass report, from what it found, what the next steps are, to how it started in the first place.

Dr Hilary Cass’s final report on NHS care for gender questioning youth has now been published

Retired consultant paediatrician Dr Cass speaking about the publication of the Independent Review of Gender Identity Services for Children and Young People, April 9

What did the Cass report broadly find?

The major review of care for gender questioning youth in England found youngsters were being let down by alack of research and evidence on the medical interventions that had become standard in the field.

As Dr Cass herself bluntly put it, the entirety of gender medicine for young people is 'built on shaky foundations'.

These included the use of controversial puberty blockers, which pause the physical changes of puberty such as breast development and facial hair growth.

It also took aim at the evidence, or lack thereof, on social transitioning, where a child is treated as if they had switch genders, for example changing pronouns and the use of cross-sex hormones in teenager.

Among the report’s 32 recommendations are a call for gender services to operate 'to the same standards' as other health services for children and young people, with 'a holistic assessment' of people referred.

Such a holistic approach would include screening for neurodevelopmental disorders such as autism, and a mental health assessment.

The Cass report also urged the NHS to change some other standards of its gender care.

This includes a review of its policy on giving children masculinising or feminising hormones from the age of 16, with the report urging 'extreme caution'.

Dr Cass said there 'should be a clear clinical rationale for providing hormones at this stage rather than waiting until an individual reaches 18'.

The use of such hormones, the review said, should be part of a research programme alongside a previously reported puberty blocker trial which is expected to be in place by December.

What did it say specifically about social transitioning?

Dr Cass's report also warned a 'more cautious approach' must be taken for children than for adolescents when it comes to social transitioning, which is where someone might change their pronouns, name and/or clothing.

When families are making decisions about social transitioning, it is important 'parents are not unconsciously influencing the child’s gender expression', the review said.

The Tavistock Centre closed a couple of weeks ago after it was found not to be 'a safe or viable long-term option'

The former president of the Royal College of Paediatrics and Child Health was appointed to lead the review in 2020

What has the Cass report recommended?

Dr Hilary Cass made 32 recommendations in total on multiple aspects of gender care for child. Here is the summary of what they are...

Research

The NHS should put in place a 'full programme of research' looking at the characteristics, interventions and outcomes of every young person presenting to the NHS gender services, with consent routinely sought for enrolment in a research study which follows them into adulthood.

Gender care is 'an area of remarkably weak evidence', the review stated, but results of studies have been 'exaggerated or misrepresented by people on all sides of the debate to support their viewpoint'.

Dr Cass said there is currently 'no good evidence on the long-term outcomes of interventions to manage gender-related distress'.

Alongside a puberty blocker trial, which is expected could be in place by December, there should be research into psychosocial (therapeutic) interventions and the use of the masculinising and feminising hormones testosterone and oestrogen.

On the latter, the review warned giving such hormones to 16-year-olds should be an approach taken with 'extreme caution'.

Care must be holistic

The care of children and young people questioning their gender identity or experiencing gender dysphoria 'needs to be holistic and personal'.

Services 'must operate to the same standards as other services seeing children and young people with complex presentations and/or additional risk factors'.

The review says assessments of needs with a view to informing 'an individualised care plan' should include screening for neurodevelopmental conditions, including autism, as well as a mental health assessment.

Age

The approach to care for the youngest children should be different to that for teenagers.

There should be no lower age limit to accessing help and support and parents and families should be helped to ensure options 'remain open and flexible for the child'.

For those yet to hit puberty, there should be a 'separate pathway' of care within each regional network of services, and young children and their parents should be prioritised for 'early discussion with a professional with relevant experience'.

There should be 'follow-through services' for 17 to 25-year-olds, rather than being transferred straight into adult services, with regional centres either extending the age range of their patients or through 'linked services, to ensure continuity of care and support at a potentially vulnerable stage in their journey'.

The review said all children should be offered 'fertility counselling and preservation' before going down the route of medical intervention.

Approach to referrals

Referrals into the now-closed Gender Identity Development Service (GIDS) at the Tavistock and Portman NHS Foundation Trust were 'unusual' in that they were accepted directly from GPs and from non-healthcare professionals including teachers and youth workers.

Dr Cass said she supports the NHS England proposal for all referrals to come via secondary care.

Social transitioning

There was 'no clear evidence' that social transition in childhood has any positive or negative mental health outcomes and 'relatively weak' evidence for effects in adolescence.

But children who socially transitioned – changing names, pronouns etc – at an earlier age or before being seen in clinic 'were more likely to proceed to a medical pathway'.

Partial transition 'may be a way of ensuring flexibility', the review said, adding that appropriately-trained clinical staff should advise on the risks and benefits of social transition 'referencing best available evidence'.

It warns parents must be careful not to unconsciously influence the child’s gender expression.

Workforce

Professionals have been reluctant to engage in the clinical care of gender-questioning children and young people due to the weak evidence in the area, a lack of consistent professional guidance and support, and long-term implications of making the wrong judgment about treatment options, the review said.

There is a need for the 'appropriate skill mix to support both individuals who require medical intervention and those who do not” as work continues to increase the available workforce.

The workforce should include a wide range of specialists including paediatricians, psychiatrists, clinical nurse specialists, social workers, specialists in neurodiversity, speech and language therapists and occupational health specialists.

Endocrinologists and fertility specialists should also feature 'for the subgroup for whom medical treatment may be considered appropriate'.

The review said NHS England must identify gaps in professional training programmes and develop training materials 'to supplement professional competencies, appropriate to their clinical field and level'.

Detransition

NHS England should consider whether a separately commissioned service is needed for people who wish to detransition – where someone discontinues or reverses a medical gender transition – given that people who regret going through this process might be hesitant to return to the same service they had previously used.

The review states that 'better services and pathways' are needed for a group of whom many are 'living with the irreversible effects of transition and no clear way to access services'.

The percentage of people treated with hormones who then detransition remains unknown because of the lack of long-term follow-up studies, but the review stated there is suggestion numbers are increasing.

Anyone detransitioning should be carefully monitored in a supportive setting, especially when coming off hormone treatments.

Private healthcare

With puberty blockers no longer being prescribed to children on the NHS, the review stated that no GP should be expected to 'enter into a shared care arrangement with a private provider' if a young person has been given access to them via that route.

The review said GPs had 'expressed concern about being pressurised to prescribe hormones after these have been initiated by private providers and that there is a lack of clarity around their responsibilities in relation to monitoring'.

Dr Cass said the Department of Health and Social Care and NHS England must 'consider the implications of private healthcare on any future requests to the NHS for treatment, monitoring and/or involvement in research', noting that a young person’s eligibility to take part in the NHS study into puberty blockers could be affected if they took puberty blockers outside the study.

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It added thatthere was no clear evidence that social transition in childhood had any positive or negative mental health outcomes.

But it noted that 'those who had socially transitioned at an earlier age and/or prior to being seen in clinic were more likely to proceed to a medical pathway'.

Has there been any reaction to report?

Responding to the report, NHS England said it had written to local NHS leaders to pause first appointment offers at adult gender clinics to young people before their 18th birthday, and is 'bringing forward its systemic review of adult gender services'.

More broadly, the health service said it was 'very grateful to Dr Cass and her team for their comprehensive work on this important review', and that it would 'set out a full implementation plan following careful consideration of this final report and its recommendations'.

Most trans rights groups have not yet seen the report, but the findings and concerns highlighted are likely to be disputed by some.

Robbie de Santos, director of campaigns and human rights at LGBTQ+ rights organisation Stonewall, had a mixed response.

'What is important, above all, is that trans and gender-diverse children get the quality healthcare that they need and deserve,' he said.

'The Cass Review can play a vital role in achieving this aim if its recommendations are implemented properly.

'Many recommendations could make a positive impact – such as expanding the provision of healthcare by moving away from a single national service towards a series of regional centres while recognising that there are many different treatment pathways that trans young people might take.

'But without due care, training or further capacity in the system, others could lead to new barriers that prevent children and young people from accessing the care they need and deserve.'

Dr Cass herself, perhaps anticipating some negative reaction, included the following notes in the report itself.

She insisted her review was 'not about defining what it means to be trans, nor is it about undermining the validity of trans identities, challenging the right of people to express themselves, or rolling back on people’s rights to healthcare'.

Instead, and addressing gender questioning children directly, she said: 'I have been disappointed by the lack of evidence on the long-term impact of taking hormones from an early age; research has let us all down, most importantly you.'

What do other doctors think?

Medical experts have broadly welcomed Dr Cass's findings.

Dr Lade Smith, president of the Royal College of Psychiatrists, said: 'Dr Hillary Cass has published a rigorous independent review.

'Crucially, it is informed by the views of people with lived experience, but also a broad range of views from stakeholders, healthcare professionals, social workers and of course, parents.

The College will now review, in detail, the recommendations of this important report and what they mean for patients, psychiatrists and mental health services. Once this work is complete, we will respond in full to its findings.'

Professor Steve Turner, president of the Royal College of Paediatrics and Child Health (RCPCH), said the review was a 'massive undertaking' and the college will 'closely consider the report’s recommendations'.

'It is essential that NHS England now provides the necessary additional guidance and support needed for paediatricians and the wider child health team to undertake their important role of caring for children who are gender questioning or experiencing gender dysphoria,' he said.

Professor Ashley Grossman, an expert in endocrinology at the University of Oxford said the new report shone a much-needed light on the use of puberty blockers in gender care.

'For many years we have been using puberty blockers in young children who are going into early puberty to delay puberty to a normal time – this has been very successful with much detailed evidence,' she said.

'This is a different situation – this set of reviews is looking at using these drugs to delay normal puberty.

'This very detailed set of analyses now suggests that there are not enough good data showing the long-term effects in children with gender dysphoria.

'More carefully run clinical trials are needed so that we can understand how and when such agents are justified and of benefit.'

Some charities have also welcomed the findings.

These include The Children’s Society, a charity allied to the Church of England which called it a 'watershed moment'.

Mark Russell, the charity's chief executive said: 'Children and young people exploring their gender identity still face unacceptable barriers in getting the support they critically need, highlighting that there are numerous oversights in how gender identity services are currently designed and delivered.

'This report should mark a watershed moment; an opportunity to dismantle the existing barriers and foster an environment which places the wellbeing and safety of all children at its heart.'

What happens now? Are NHS gender care services for children still running?

Gender care services for young people in England and Wales will continue as usual, while the NHS considers the Cass report.

Just weeks before final report came out, the NHS restricted the use of puberty blockers citing a lack of evidence on their 'safety or clinical effectiveness'.

However, NHS England's decision is not an outright ban on the puberty blockers completely.

Some 100 children currently on the drugs via the NHS will be allowed to continue their treatment to its conclusion and there are plans, as supported by the Cass report, for a clinical trial in their use in the future.

Additionally, in a sign of changes being underway the NHS's old Gender Identity Development Service (GIDS) at the Tavistock and Portman NHS Foundation Trust shut its doors two weeks ago.

This was followed by two new regional hubs opening in London and the north of England in an effort to move away from a single-service model.

NHS bosses hope to open seven or eight such centres in the future.

Will the report change how private gender clinics operate?

No, at least not directly.

As they are not under NHS purview, private clinics in England can still dish out puberty blockers and hormones to children as they have done in the past.

However, the Cass report's findings on a lack of evidence on the safety and effectiveness of such treatments will likely be used by campaigners who are calling for such private gender clinics to be restricted.

The review itself has stated that no GP should be expected to 'enter into a shared care arrangement with a private provider' if a young person has been given access to puberty blockers via that route.

It added GPs had 'expressed concern about being pressurised to prescribe hormones after these have been initiated by private providers and that there is a lack of clarity around their responsibilities in relation to monitoring'.

Dr Cass said the Department of Health and Social Care and NHS England must 'consider the implications of private healthcare on any future requests to the NHS for treatment, monitoring and/or involvement in research'.

Her review also noted that a young person’s eligibility to take part in the NHS study into puberty blockers could be affected if they took puberty blockers provided by an external source.

Is the report for England and Wales only?

Yes, the report was commissioned by NHS England which also runs gender care services for under 18s in Wales.

Therefore, gender care services in other parts of the UK, like those in Scotland,are not in its purview.

However, it will likely be referenced in debates about those services in the future.

Indeed, Northern Ireland has already said it will follow England's lead on the use of puberty blockers following the announcement of the change last month.

How did the Cass report get underway?

The Cass report was commissioned by NHS England in September 2020 to makerecommendations about NHS services for gender-questioning children and young people.

It was led by Dr Hilary Cass, former president of the Royal College of Paediatrics and Child Health.

NHS England said at the time that the review has been established 'in response to a complex and diverse range of issues'.

One of these was a massive surge in referrals to the NHS Gender Identity Development Service (GIDS) over the previous decade.

Referrals for GIDS, hosted at the Tavistock and Portman NHS Foundation Trust, went from just under 250 in 2011/12 to more than 5,000 in 2021/22.

Keira Bell who previously took the clinic to the High Court, claiming she had not been challenged enough, before being prescribed puberty blockers at just 16 called it 'a step in the right direction'

During the same period wait times for patients in the system ballooned, with some waiting years to access care.

At the same time practices at GIDS were coming under increasing scrutiny after former patients and whistleblowing staff claimed youngsters were being rushed onto medication like puberty blockers despite concerns over their use.

This included Keira Bell who previously took the clinic to the High Court, claiming she had not been challenged enough, before being prescribed puberty blockers at just 16.

These concerns, which have been largely validated by the Cass review, surrounded a lack of evidence regarding the safety of their use in patients and uncertainty about their long-term impact on patients' health.

Revealed: Timeline of what has happened since the Cass report was commissioned nearly four years ago

Here is a timeline of events since it the Cass report was launched almost four years ago.

2020

September: The Independent Review of Gender Identity Services for Children and Young People is commissioned by NHS England and NHS Improvement to make recommendations about NHS services for gender-questioning children and young people.

Led by Dr Hilary Cass, former president of the Royal College of Paediatrics and Child Health, it is known as the Cass Review.

NHS England says it has been established 'in response to a complex and diverse range of issues' including the significant rise in referrals to the Gender Identity Development Service (GIDS) at the Tavistock and Portman NHS Foundation Trust from just under 250 in 2011/12 to more than 5,000 in 2021/22.

October and November: The Care Quality Commission (CQC) inspects GIDS, which is the only service available in England for children and young people with gender dysphoria, also treating children and young people from Wales.

2021

January: The CQC publishes its inspection report which rates the service inadequate overall.

The watchdog says the service is difficult to access, with young people waiting more than two years for their first appointment, and that staff do not develop holistic care plans for patients, with 'significant variations in the clinical approach of professionals' and no clarity in records on why decisions had been made.

2022

March: Dr Cass publishes her interim report, saying a 'fundamentally different service model is needed which is more in line with other paediatric provision', and concluding that a sole provider of such services is 'not a safe or viable long-term option".

July: The NHS announces GIDS will close and be replaced with a regional network, aimed to be up and running by spring 2023.

2023

The deadline for the regional clinics to be operating is pushed back amid what NHS England describes as the 'complex' set-up of the 'completely new service'. The new aim is spring 2024.

2024

March: NHS England confirms children will no longer be prescribed puberty blockers at gender identity clinics, saying there is not enough evidence to support their 'safety or clinical effectiveness" and that they would only be available to children as part of clinical research trials.

April: New regional hubs open as the GIDS at Tavistock officially closes.

Led by London's Great Ormond Street Hospital and Alder Hey Children's Hospital in Liverpool, NHS England hopes they will be the first of up to eight specialist centres as part of the north and south hubs over the next two years.

The Cass Review's final report is published.

Everything you need to know about the Cass report (2024)
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